PureGenomics Multivitamin by Pure Encapsulations

PRO's

• Uses high-quality, bioavailable (methylated) forms of most nutrients for better absorption
• Third-party tested
• No contaminants, heavy metals, or allergens

CON's

• Company got purchased by Nesté in 2007 and is now a division of Nestlé Health. Not too worrying as they also own Vital Proteins and Garden of Life which are two other brands known for high quality ingredients
• There are a few unnecessarily high dosages of vitamins and minerals
• Missing some vital nutrients which means you have to take multiple forms of supplements to get all the nutrients you need.
• Uses a few synthetic compounds/elements

WHY it gets our stamp of approval:

1. Non-GMO & no pesticides or herbicides 
2. No Artificial sweeteners, Added sugar, Erythritol, Monk fruit, MSG
3. Natural healthy ingredients
4. Very few synthetic elements/compounds which is top percentile compare to other multivitamins on the market
5. No known harmful chemicals, contaminants, or additives

If taking other medications or drugs use their Drug Nutrient Interaction Checker

The ingredients listed are generally regarded as safe and beneficial, though some considerations apply:

• Chromium (as chromium polynicotinate): The dosage here is 200 mcg, which is 571% of the daily value (DV). Although chromium supplementation is considered safe for most people, very high doses can cause side effects like gastrointestinal upset or impaired kidney function in sensitive individuals.

• Vitamin E (as d-alpha tocopherol succinate): At 134% of the DV, this synthetic form of Vitamin E may not be harmful, but over-supplementation can potentially interfere with Vitamin K, increasing bleeding risk.

• Vitamin K1 (as phylloquinone) and Vitamin K2 (as menaquinone-7): Vitamin K is necessary for blood clotting, but people on anticoagulants (e.g., warfarin) should consult a doctor before taking Vitamin K supplements.

Overall, these vitamins and minerals in this formula are in acceptable ranges, but individuals with specific health conditions should always consult with healthcare professionals.

Potential Concerns or Improvements

• Vitamin A (as acetate and beta carotene): This formula uses a combination of Vitamin A acetate (synthetic form) and beta carotene. Beta carotene is a good source of Vitamin A and is less likely to be toxic compared to preformed Vitamin A like acetate. A higher ratio of natural beta carotene might be preferable for better safety.

• Vitamin E (as d-alpha tocopherol succinate): Although labeled as “d-alpha,” which indicates a more natural form, the succinate is a processed version. Natural mixed tocopherols (including gamma-tocopherol) might provide more comprehensive antioxidant benefits.

• Vitamin B12 (as adenosylcobalamin and hydroxocobalamin): This combination is better compared to cyanocobalamin (a more common but synthetic form). Both adenosylcobalamin and hydroxocobalamin are biologically active forms of B12, enhancing bioavailability.

• Choline (as choline bitartrate): Choline bitartrate is effective, but phosphatidylcholine, which is derived from lecithin, might be more beneficial as it offers additional phospholipids helpful for cellular health.

Missing Vitamins or Minerals

This formula is fairly comprehensive, but there are a few elements that could enhance longevity and overall health:

• Magnesium: This essential mineral is missing in the formula. Magnesium is crucial for numerous enzymatic reactions, muscle relaxation, and energy production. It would be beneficial to include a highly bioavailable form like magnesium glycinate.

• Calcium: There is no calcium in the formula. While many people may get adequate calcium from their diet, supplementation may be necessary for those at risk of osteoporosis or with low dietary intake.

• Omega-3 Fatty Acids (EPA/DHA): While not typically found in standard multivitamins, omega-3s are critical for cardiovascular health and reducing inflammation. Including this in a supplement regimen could be important for longevity.

• Potassium: Although present in many diets, potassium plays a key role in regulating blood pressure and cardiovascular health. A small amount could complement the iodine and other electrolytes included.
  

Conclusion

• Harmful Ingredients: None of the ingredients appear harmful at the dosages listed, but people with specific health conditions should seek professional guidance before using.
• Better Forms: Some ingredients could be in more natural forms, such as using more beta carotene over acetate for Vitamin A and including natural mixed tocopherols for Vitamin E.
• Missing Nutrients: The absence of magnesium, calcium, and omega-3 fatty acids might make this multivitamin less comprehensive for those seeking optimal health and longevity.
• Synthetic Compounds: Some synthetic compounds are used, but they are typical for supplements and generally considered effective and safe.